This is a singlecenter parallel group randomized controlled trial with preintervention, postintervention, retention, and followup tests. The effects of ai chi for balance in individuals with chronic. A convenience sample of 103 people, 4 to 24 weeks mean, 12. A randomized controlled trial of rehabilitation at home after stroke in southwest stockholm. In both groups, the interventions were targeted to the distal upper extremity and standard occupational therapy was administered. This randomized control study, investigated the influence of pretreatment statin and its subsequent withdrawal on outcome after acute ischemic stroke.
Ethics reporting practices in randomized controlled trials of. Pretreatment with statins has been shown to reduce brain injury in cerebral ischemia. As with pasta, there was no significant change in doortoneedle time, suggesting. Adequate reporting of ethicsrelated research methods promotes convergence on best ethics practices. Article information, pdf download for a randomized controlled trial of leisure. However, a recent randomized controlled trial demonstrated that acupuncture has no specific efficacy in stroke rehabilitation.
The effectiveness of locomotor therapy using robotic. Effects of tai chi yunshou exercise on communitybased stroke. Mental practice with motor imagery in stroke recovery. Patients aged 1880 years with acute ischaemic stroke and proximal cerebral artery occlusion were randomly assigned to receive either intravenous thrombolysis alone ivt group or intravenous thrombolysis plus mechanical thrombectomy ivtmt group. Subjects were randomly allocated to the leisure rehabilitation group, the conve. Understanding and misunderstanding randomized controlled trials, with nancy cartwright, social s. This is an open, blinded endpoint, randomized controlled trial carried out from january 2011 to august 20.
A metaanalysis of shamcontrolled randomized clinical trials concluded that there is insufficient evidence to support the use of acupuncture for functional. To explore the effectiveness of modified sittostand training on balance function in hemiplegic stroke patients. Intensive speech and language therapy in patients with chronic aphasia after stroke. Jan 27, 2020 the effect of aquatic therapy on postural balance and muscle strength in stroke survivorsa randomized controlled pilot trial. Apr 19, 2012 scalp acupuncture twisting manipulation for treatment of hemiplegia after acute ischemic stroke in patients. Types of trials individually randomized trials eligible individuals are randomized conventional medical rcts and many behavioral rcts selfselection of persons volunteering for enrollment cluster randomized trials clusters e. Occupational performance coaching for stroke survivors. A 10 mm hg difference in sbp has been equated to a 24% difference in stroke risk among black individuals 8 and every 1 mm hg elevation in sbp to a 1% increase in stroke mortality in the general population. Doubleblind, parallel group, randomized controlled trial. Randomized clinical trial an overview sciencedirect topics.
Participants were randomized into groups that varied in total dosage of therapy i. A randomized controlled trial or randomized control trial. Objective tailoring stroke information and providing reinforcement opportunities are two strategies proposed to enhance the effectiveness of education. A trained researcher, blinded to the group allocation, will collect the written consent and the outcome measures at baseline, postintervention after the 12week intervention, and at the 16week followup, i. Effects of prism adaptation pa to alleviate neglect have been reported. We examined the feasibility of study procedures and explored the potential efficacy of occupational performance coaching for stroke survivors opcstroke, an intervention designed to improve participation after stroke. The lots care trial was a pragmatic, multicenter, cluster randomized, controlled trial of a complex intervention designed to provide a structured but individualized care planning process that encompassed the range of problems commonly encountered by people recovering from a stroke and delivered by sccs working in the community. However, either small groups or no control group were included. Randomized controlled trial of early rehabilitation after. Randomized controlled trials rcts page 2 in a simple rct, the unit of analysis for the intervention and for the random assignment is the same.
Methods we conducted a multicentre, prospective, randomised, open label, blinded, controlled clinical trial enrollingpatients with an onset of acute stroke within 7 days from five hospitals in china. A total of 600 adult patients with severe stroke will be enrolled in 12 study sites in china, and randomized to standard full en, modified full en, or permissive underfeeding. A frequent disorder after stroke is neglect, resulting in a failure to report or respond to contralesional stimuli. Efficacy of lowfrequency repetitive transcranial magnetic. Effects of tai chi yunshou exercise on communitybased. In this cluster randomized controlled trial, we defined the balance rehabilitaion training as positive control, which is known as standard method for the balance rehabilitation of the stroke surivors according the guideline. The quality of reporting of randomized controlled trials of. Effect of an enhanced paramedic acute stroke treatment. In a randomized controlled trial rct, 14 sessions of supported standing, added with flexible duration and schedules to conventional rehabilitation within nine weeks after stroke onset, did not significantly improve functional status. Effect of folate and mecobalamin on hip fractures in. A metaanalysis of sham controlled randomized clinical trials concluded that there is insufficient evidence to support the use of acupuncture for functional recovery after stroke 18. The study included 46 stroke survivors who were randomized to a smart glove sg group or a conventional intervention con group. Data collection was performed in a research laboratory located in a rehabilitation hospital.
Pdf meaningful taskspecific training mtst for stroke. This study is aimed at evaluating the quality of reporting of. Rehabilitation of neglect is important, given the negative influence on motor recovery, independence in selfcare, transfers, and locomotion. We explored the effectiveness of mirror therapy mt in the treatment of unilateral neglect in stroke patients. However, there is still a lack of enough evidence to recommend the routine use of ea for stroke. The randomized controlled trial article pdf available in nephron clinical practice 14. Mirror therapy in unilateral neglect after stroke must trial. In addition to conventional therapy, the experimental group received 16 hours of truncal exercises. Unilateral vs bilateral hybrid approaches for upper limb rehabilitation in chronic stroke. A randomised, openlabel, blindedendpoint, controlled trial in a healthcare setting. A multisite scandinavian trial 7 randomized 942 patients with suspected stroke or transient ischemic attack to a higher vs a standard response level after multidisciplinary training and reported a thrombolysis rate of 24% compared with 10% among the control group. The quality of reporting of randomized controlled trials. Seven hundred and four participants were assessed for. A total of 33 participants mean 35 days post onset were randomly assigned to an experimental group n 18 or a control group n 15.
An assessorblinded randomized controlled trial was carried out at a stroke rehabilitation hospital. Randomized controlled trial of a comprehensive stroke education program for patients and caregivers. Our randomized trial involving patients with acute ischemic stroke and dyslipidemia did not show any superiority of early statin therapy within 24. A superiority parallelgroup randomized controlled trial, with concealed allocation and blinded assessments, will be carried out. A randomized controlled trial article pdf available in topics in stroke rehabilitation 193. The study design was a prospective multicenter, randomized control trial in parallel groups with equal randomization.
Participants will be randomly allocated to either cmill therapy or the overground falls program for 5 weeks. This randomized controlled trial evaluated the therapeutic benefit of mental practice with motor imagery in stroke patients with persistent upper limb motor weakness. Phonomotor versus semantic feature analysis treatment for. A randomized controlled trial of leisure rehabilitation after stroke. Rct is a type of scientific often medical experiment that aims to reduce certain sources of bias when testing the effectiveness of new treatments. Before we initiated the patch trial in 2009, a search of clinicaltrials. Mirror therapy in unilateral neglect after stroke must. Grv is defined as the fluid remaining in the stomach at a point in time during enteral nutrition feeding. What do randomized controlled trials say about virtual. The effect of warfarin administration time on anticoagulation. Randomised controlled trial of an education and support. Purpose to evaluate the efficacy and safety of ginkgo biloba extract gbe in acute ischaemic stroke and its impact on the recurrence of vascular events. This work is licensed under a creative commons attribution. Mirror therapy has also been shown effective in the treatment of complex regional pain syndrome and phantom limb pain.
There is evidence to suggest that mental rehearsal of movement can produce effects normally attributed to practising the actual movements. Methods this is a parallel group, four arm, single blind, phase i, randomized control trial of four dosages of upper extremity therapy delivered in an outpatient setting during the chronic phase after stroke. Based on a sample of rcts of physical therapy interventions after stroke, our objectives were to investigate the reporting of multiple ethicsrelated features and its variation over time, as well as the characteristics of the. Effects of modified sittostand training on balance control. Pdf download for early mobilization of mildmoderate intracerebral. Design, setting, and patients a doubleblind, randomized controlled study of 628 consecutive patients aged 65 years or older with residual hemiplegia at least 1 year following first ischemic stroke, who were recruited from a single japanese hospital from april 1, 2000, to may 31, 2001. On april 1, 2016, we searched medline pubmed from jan 1, 1950. The effect of aquatic therapy on postural balance and muscle strength in stroke survivorsa randomized controlled pilot trial. We included stroke patients with thalamic and parietal lobe lesions with unilateral neglect 48 hours after stroke. The effects of ai chi for balance in individuals with.
Caregiverdelivered stroke rehabilitation in rural china. Compared tai chi yunshou exercise with positive control on the physical and mental health of stroke survivors, we found. Randomized controlled trial of a comprehensive stroke. A brief description a randomized controlled trial rct is a way of doing impact evaluation in which the population receiving the programme or policy intervention is chosen at random from the eligible population, and a control group. Effects of aerobic training on physical activity in people.
This study is aimed at evaluating the quality of reporting of randomized controlled trials rcts. Rodgers h1, atkinson c, bond s, suddes m, dobson r, curless r. Mehrholz and k chamari, title randomized controlled trial speeddependent treadmill training in ambulatory hemiparetic stroke patients. Acupuncture is widely used to enhance stroke recovery in eastern countries. Baduanjin exercise intervention for community adults at risk. Study protocol for a randomized controlled trial article pdf available in bmc complementary and alternative medicine 121. Mechanical thrombectomy after intravenous alteplase versus. Caregiverdelivered stroke rehabilitation in rural china stroke. Scalp acupuncture twisting manipulation for treatment of hemiplegia after acute ischemic stroke in patients. Effect of folate and mecobalamin on hip fractures in patients. Singleblinded, 2armed, randomized controlled trial. A randomized controlled trial author links open overlay panel chungshan hung phd a kehchung lin scd, otr b c wanying chang ms d wenchih huang ms e yaju chang phd f chialing chen md, phd g h kaiping grace yao phd i yayun lee phd j.
Randomized controlled trial of early versus delayed statin. The present study was a singleblinded, randomized controlled trial. Randomized controlled trial speeddependent treadmill. In patients with subacute ischemic stroke, 1hz lowfrequency rtms on contralesional premotor cortex along with. The opens trial is a multicenter randomized controlled study. Randomized controlled trials85 evaluation, we argue that there needs to be a consensus among persons recognized as experts in what they label credible.
These patients were randomly assigned into two groups. This is a singlecenter parallel group randomized controlled trial with pre intervention, postintervention, retention, and. Ethics reporting practices in randomized controlled trials. Upright positioning at the acute phase of ischemic stroke. Individually randomized trials eligible individuals are randomized conventional medical rcts and many behavioral rcts selfselection of persons volunteering for enrollment cluster randomized trials clusters e. Dapackd is a multinational, multicentre, eventdriven, randomized, doubleblind, parallelgroup, placebocontrolled trial that will recruit. Ginkgo biloba extract improved cognitive and neurological. Thrace is a randomised controlled trial done in 26 centres in france. Hence to evaluate the effect of grv on the en a randomized controlled trial to evaluate the incidence of regurgitation and aspiration was conducted on 210 patients with severe stroke undergoing en therapy.
Randomized controlled trial of truncal exercises early. This study aimed to evaluate the effects of an education package which utilised both strategies on the knowledge, health and psychosocial outcomes of stroke patients and carers. Methods we conducted a multicentre, prospective, randomised, open label, blinded, controlled clinical trial enrollingpatients with an onset of acute stroke within 7 days from five hospitals in china jiangsu province. Randomized controlled trial of truncal exercises early after. Optimizing early enteral nutrition in severe stroke opens. Following are the inclusion and exclusion criteria for the trial. A randomized controlled trial on rehabilitation through caregiverdelivered nurseorganized service programs for disabled stroke patients in rural china the recover trial. Download fulltext pdf meaningful taskspecific training mtst for stroke rehabilitation. In this pilot randomized controlled trial, 21 participants were randomized to receive the intervention or usual care. We hypothesized that early rehabilitation, within 48 hours of stroke, would improve survival and functional outcomes in patients with intracerebral. Patients were assigned to daily oral treatment with 5 mg of. In this chapter, we will describe the elements of an rct that make it more.
Mar 27, 2017 we examined the feasibility of study procedures and explored the potential efficacy of occupational performance coaching for stroke survivors opcstroke, an intervention designed to improve participation after stroke. The purpose of this study was to determine whether motivational interviewing, a patientcentered counseling technique, can benefit patients mood 3 months after stroke 29. Motivational interviewing early after acute stroke. The reporting of this study conforms to the strengthening the reporting of observational studies in epidemiology recommendations. This was a randomized, controlled, doubleblinded trial in the neurology department of a university hospital and occupational therapy unit of a rehabilitation institute. Rationale and protocol of the dapagliflozin and prevention. Clinical effects of scalp electrical acupuncture in stroke. Shoulder taping reduces injury and pain in stroke patients. Reducing hypertension in a poststroke black and hispanic. Platelet transfusion versus standard care after acute stroke.
Baduanjin exercise intervention for community adults at. Primary prevention for risk factors of ischemic stroke with baduanjin exercise intervention in the community elder population. Georges university hospital, london, uk, 2division of neonatology, department of pediatrics, mount sinai hospital, toronto, on, 3institute of health policy, management and evaluation, university of toronto, toronto, on, canada, 4department of clinical. Pdf a randomized controlled trial of very early rehabilitation in. Design multisite, randomised trial comparing usual care with an. Early mobilization of mildmoderate intracerebral hemorrhage. Volume 100, issue 12, december 2019, pages 22252232. Electroacupuncture ea, as an extension technique of acupuncture based on traditional acupuncture combined with modern electrotherapy, is commonly used for stroke in clinical treatment and researches. Article pdf available in international journal of stroke 115 may 2016 with 394 reads. Passive standing as an adjunct rehabilitation intervention. A trial similar to ours a canadian primary care randomized controlled trial recruiting all warfarin users reported a 70% baseline ttr. Understanding and misunderstanding randomized controlled. A randomized controlled trial rct is an experimental form of impact evaluation in which the population receiving the programme or policy intervention is chosen at random from the eligible population, and a control group is also chosen at random from the same eligible population.
This is a singlecenter parallel group randomized controlled trial with preintervention, postintervention, retention, and. Effects of virtual realitybased rehabilitation on distal. Effects of modified sittostand training on balance. Effects of modified sittostand training on balance control in hemiplegic stroke patients. For example, when evaluating a programme that provides nutrition to individuals, individuals might be randomly assigned to receive nutritional supplements.